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Clonazolam (also referred to as Clonitrazolam) is a unique depressant substance of the benzodiazepine chemical course which generates anxiolytic, sedative, muscle mass depressant, and amnesic impacts when administered. This substance is a unique study chemical derivative of the FDA-approved drugs clonazepam (Klonopin, Rivotril) and also alprazolam (Xanax). Clonazolam is reported to be approximately 2.5 x as powerful as alprazolam.

Clonazolam is a medicine of the benzodiazepine course. Benzodiazepine medications have a benzene ring fused to a diazepine ring, which is a 7 membered ring with both nitrogen components located at R1 as well as R4. The benzyl ring of clonazolam is substituted at R8 with a nitro team, NO2-. Better, the diazepine ring is bound at R6 to a 2-chlorinated phenyl ring.

Clonazolam also contains a 1-methylated triazole ring integrated to and also including R1 as well as R2 of its diazepine ring. Clonazolam belongs to a course of benzodiazepines containing this merged triazole ring, called triazolobenzodiazepines, differentiated by the suffix “-zolam.” Clonazolam is additionally a nitrobenzodiazepine, a subclass of benzodiazepines which have a nitro (NO2-) team. Various other nitrobenzodiazepines consist of clonazepam as well as flunitrazepam.

The synthesis of clonazolam was first reported in 1971. It was described as the most active compound in the collection evaluated. Clonazolam is considered to be highly potent, and also problems have actually been increased that it and flubromazolam may position fairly greater threats than other developer benzodiazepines due to their capacity to produce solid sedation and also memory loss at dental doses as reduced as 0.5 mg, or 500 micrograms ( µg). It is reported to have a medium-length onset of activity (20 – 60 minutes).

Very little is understood about this compound, however, it has recently become conveniently available with on the internet research study chemical vendors where it is being marketed as a designer drug. Due to its exceptionally high strength, it is typically discovered on blotter paper or in volumetrically dosed solutions. Consumption of raw clonazolam powder is unsafe due to its microgram-range effectiveness as well as the ease in which it can lead to multi-day outages.